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Using data from the Harvard Aging Brain Study, Kelsey Biddle and colleagues found that low social engagement is associated with worsening cognition in older adults who are cognitively normal but have neuroimaging evidence of Alzheimer’s disease pathophysiologic change. These findings emphasize the importance of social engagement as a resilience or vulnerability marker in older adults at risk of cognitive impairment due to AD and support recommendations promoting social engagement in older adults. [Article]

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