Welcome to the Neuropsychiatry of Aging Research group’s webpage. Our collaborative research investigates the neurology of emotional and social function in healthy older adults and those affected by Alzheimer’s disease. We work within the Harvard Aging Brain Study and other large observational studies to define emotional, behavioral and pathological changes that occur at the earliest stages of Alzheimer’s disease, prior to the onset of cognitive impairment. These changes include traditional neuropsychiatric symptoms such as anxiety and depression as well as subtle changes in social function.
By recognizing these early symptoms in older adults, we seek to enhance the detection of Alzheimer’s disease and advance treatment options to preserve cognitive and mental health in late-life.
LATEST PUBLICATIONS AND PRESENTATIONS
Associations of Widowhood and β-Amyloid With Cognitive Decline in Cognitively Unimpaired Older Adults by Kelsey Biddle et al. published in JAMA Network Open, February 2020.
Social Engagement and Amyloid-Beta-Related Cognitive Decline in Cognitively Normal Older Adults published in the American Journal of Geriatric Psychiatry, May 2019
Kelsey Biddle presented research on the Interactive Adverse Effects of Widowhood and Amyloid-Beta on Cognitive Decline in Cognitively Normal Older Adults at the Alzheimer’s Association International Conference in Los Angeles, July 2019.