Welcome to the Neuropsychiatry of Aging Research group’s webpage. Our collaborative research investigates the neurology of emotional and social function in healthy older adults and those affected by Alzheimer’s disease. We work within the Harvard Aging Brain Study and other large observational studies to define emotional, behavioral and pathological changes that occur at the earliest stages of Alzheimer’s disease, prior to the onset of cognitive impairment. These changes include traditional neuropsychiatric symptoms such as anxiety and depression as well as subtle changes in social function.
By recognizing these early symptoms in older adults, we seek to enhance the detection of Alzheimer’s disease and advance treatment options to preserve cognitive and mental health in late-life.
LATEST PUBLICATIONS AND PRESENTATIONS
Specific Association of Worry With Amyloid-β But Not Tau in Cognitively Unimpaired Older Adults
Published in the American Journal of Geriatric Psychiatry, May 2024.
Nancy Donovan, MD is interviewed by the New York Times about the effects of loneliness on the aging brain.
Published in the New York Times, May 2024.
Social activity mediates locus coeruleus tangle-related cognition in older adults
Published in Molecular Psychiatry, January 2024.